SPYRE THERAPEUTICS, INC. (SYRE) valuation

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Share price $50.44 · As of last filing 2026-03-31

Price-to-Earnings

P/E · Trailing Diluted
—
P/E history →

Price-to-Free-Cash-Flow

P/FCF · Trailing
—
P/FCF history →

Free-Cash-Flow Yield

FCF Yield · Trailing
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FCF Yield history →

Enterprise-Value-to-EBITDA

EV/EBITDA · Trailing
-17.36×
EV/EBITDA history →

Price-to-Sales

P/S · Trailing
—
P/S history →

Price-to-Book

P/B · Latest filing
6.53×
P/B history →

What these ratios mean & how they're built: see the valuation ratios glossary on the Financials methodology page — per-ratio definitions and the exact us-gaap concepts behind each numerator and denominator.

Sources. Denominators come from SEC EDGAR XBRL filings for SYRE (CIK 0001636282); analyst growth forecasts come from analyst consensus. Filing-anchored figures are rendered server-side at the split-adjusted close on the latest reported period-end — so every ratio reconciles to the same filing as every other figure on this page — and the share price, six ratio cards, EPV gap, and reverse-DCF outputs above re-anchor on the most recent daily close in the browser when JavaScript is enabled. The "Full calculation trail" sections stay anchored to the period-end close so the line-by-line arithmetic still reconciles. Per-share denominators are split-adjusted to today's share count.

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