Prime Medicine, Inc. (PRME) Stock Total Returns

Growth of $10,000 chart

2022-10-20 to 2026-06-03
to
$
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Investment Performance

Final Value
$2,043
Total Return
-79.57%
CAGR
-35.52%
Dividends
$0.00
Yield on Cost
0.00%

Rolling Returns

1-Month (21 Trading Days)
Average-0.26%
Median-5.79%
Best+214.05%
Worst-47.72%
% of Windows Positive39.7%
1-Year (252 Trading Days)
Average-22.99%
Median-51.87%
Best+216.24%
Worst-83.94%
% of Windows Positive26.7%
3-Year (756 Trading Days)

Risk Metrics

Maximum Drawdown -94.55%
Average Drawdown -65.25%
Drawdown Duration 898 Trading Days (Unrecovered)
Sortino Ratio -0.08
Calmar Ratio -0.38
CVaR (5%) -10.64%

Yearly Returns

Year Percentage Abs. Return Dividends Taxes Trans. Costs
2026 partial -9.51% (-21.10% ann.) $950.99 $0.00 $0.00 $0.00
2025 +18.84% +$1883.57 $0.00 $0.00 $0.00
2024 -67.04% $6704.30 $0.00 $0.00 $0.00
2023 -52.31% $5231.43 $0.00 $0.00 $0.00
2022 partial +20.88% (+165.31% ann.) +$2088.48 $0.00 $0.00 $0.00

Market Regimes

about
Regime Period Percentage Annual Abs. Return Dividends Taxes Trans. Costs
Inflation shock / duration crash / aggressive tightening partial October 20, 2022 – November 9, 2022 +27.00% +7766.09% +$2700.07 $0.00 $0.00 $0.00
Disinflation rebound / AI-led narrow bull / higher-for-longer November 10, 2022 – September 17, 2024 -80.55% -58.67% $8055.42 $0.00 $0.00 $0.00
Disinflationary easing / resilient growth / AI capex under oil-shock test partial September 18, 2024 – June 3, 2026 -21.11% -12.98% $2110.56 $0.00 $0.00 $0.00

Dividend History

Date Per Share Yield %
Total 0 payments
No dividends recorded.

All calculations use split-adjusted closing prices. Dividends are reinvested on the ex-dividend date at that day's closing price.

For each rolling window, returns are calculated at every possible starting point:

return = (value[i] ÷ value[i − windowSize] − 1) × 100

Windows
1-month = 21 trading days, 1-year = 252 trading days, 3-year = 756 trading days.
Statistics
Average: arithmetic mean. Median: middle value when sorted. Best / Worst: max and min. % Positive: share of windows with return > 0.

The series is segmented by calendar year:

return = (endValue ÷ startValue − 1) × 100

startValue is the last value of the prior year (or the first value for the initial year). Partial first/last years are flagged. Dividends, taxes, and transaction costs are scaled proportionally to the initial investment.

LNTH

CAGR 27.93% Total 1380.80% Final $148,080
2015-06-25 — 2026-06-03
TBRG

CAGR 3.60% Total 133.78% Final $23,378
2002-05-21 — 2026-06-03
CMDB

CAGR 18.55% Total 20.37% Final $12,037
2025-05-01 — 2026-06-03