AGIOS PHARMACEUTICALS, INC. financials
Source: EDGAR filings · Built 2026-06-02T02:15:55Z
Key metrics by reporting period
Up to six most-recent periods side-by-side. Rows are the curated key lines — revenue, margins, cash, debt, equity, cash-flow totals, plus the derived and valuation metrics we compute on top. For every tag a filer reported in one period, use the single-filing drilldown below.
Derived Metrics
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Free Cash Flow | -377.29M | -391.53M | -297.06M | -314.69M | -413.64M | -305.20M |
| EBITDA | -466.93M | -420.04M | -384.89M | -380.65M | -369.62M | -326.52M |
| Working Capital | 859.85M | 884.44M | 765.88M | 770.14M | 1.00B | 542.28M |
| Net Debt | -48.92M | -19.26M | -16.21M | -53.60M | -106.03M | -22.24M |
| Gross Margin | 88.26% | 88.59% | 89.26% | 88.03% | — | — |
| Operating Margin | -873.87% | -1166.47% | -1459.52% | -2732.07% | — | — |
| Net Margin | -764.01% | 1845.92% | -1312.63% | -1627.82% | — | — |
| Return on Equity (ROE) | -34.60% | 43.72% | -43.41% | -21.06% | 124.21% | -81.94% |
| Return on Assets (ROA) | -31.82% | 40.51% | -37.57% | -18.71% | 111.61% | -38.38% |
| Current Ratio | 11.46× | 11.90× | 12.27× | 13.30× | 17.79× | 6.74× |
| Debt-to-Equity | 0.03× | 0.04× | 0.09× | 0.08× | 0.08× | 0.26× |
| Effective Tax Rate | 0.25% | 6.16% | 0.00% | 0.00% | — | — |
| Cash Conversion Ratio | 0.90× | -0.58× | 0.84× | 1.34× | -0.25× | 0.89× |
| Accruals Ratio | -0.03× | 0.64× | -0.06× | 0.06× | 1.40× | -0.04× |
| SBC % of Revenue | 97.27% | 117.40% | 166.89% | 346.18% | — | — |
| CapEx Coverage | -86.42× | -231.36× | -296.36× | -59.38× | -64.46× | -20.13× |
| Free Cash Flow Per Share | $-6.51 | $-6.76 | $-5.34 | $-5.74 | $-6.84 | $-4.42 |
Valuation Metrics
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| P/E Trailing (Diluted) | — | 2.82× | — | — | 1.24× | — |
| P/S | 29.45× | 51.46× | 46.45× | 108.53× | — | — |
| P/B | 1.33× | 1.22× | 1.54× | 1.40× | 1.38× | 7.52× |
Income Statement
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Revenue from Contract with Customer, Excluding Assessed Tax | 54.03M | 36.50M | 26.82M | 14.24M | 0 | 0 |
| Cost of Goods and Services Sold | 6.34M | 4.17M | 2.88M | 1.70M | 0 | 0 |
| Research and Development Expense | 339.54M | 301.29M | 295.53M | 279.91M | 256.97M | 220.81M |
| Selling, General and Administrative Expense | 180.28M | 156.78M | 119.90M | 121.67M | 121.44M | 115.11M |
| Operating Income (Loss) | -472.13M | -425.74M | -391.49M | -389.05M | -378.42M | -335.92M |
| Income Tax Expense (Benefit) | -1.02M | 44.24M | 0 | 0 | — | — |
| Net Income (Loss) Attributable to Parent | -412.78M | 673.73M | -352.09M | -231.80M | 1.60B | -327.37M |
| Earnings Per Share, Basic | $-7.12 | $11.86 | $-6.33 | $-4.23 | $26.55 | $-4.74 |
| Weighted Average Number of Shares Outstanding, Basic | 57.97M | 56.81M | 55.65M | 54.79M | 60.45M | 69.00M |
| Earnings Per Share, Diluted | $-7.12 | $11.64 | $-6.33 | $-4.23 | $26.55 | $-4.74 |
| Weighted Average Number of Shares Outstanding, Diluted | 57.97M | 57.89M | 55.65M | 54.79M | 60.45M | 69.00M |
Balance Sheet
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Cash and Cash Equivalents, at Carrying Value | 89.13M | 76.25M | 88.20M | 139.26M | 203.13M | 127.44M |
| Assets, Current | 942.05M | 965.60M | 833.84M | 832.77M | 1.06B | 636.68M |
| Assets | 1.30B | 1.66B | 937.12M | 1.24B | 1.44B | 852.95M |
| Liabilities, Current | 82.21M | 81.16M | 67.95M | 62.63M | 59.83M | 94.39M |
| Liabilities | 104.11M | 122.24M | 126.10M | 137.90M | 145.76M | 453.45M |
| Stockholders' Equity Attributable to Parent | 1.19B | 1.54B | 811.02M | 1.10B | 1.29B | 399.50M |
| Common Stock, Shares, Outstanding | 58.45M | 57.16M | 55.95M | 55.04M | 54.33M | 69.29M |
Cash Flow Statement
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Net Cash Provided by (Used in) Operating Activities | -372.98M | -389.84M | -296.06M | -309.48M | -407.32M | -290.76M |
| Payments to Acquire Property, Plant, and Equipment | 4.32M | 1.69M | 999.00K | 4.88M | 5.74M | 14.11M |
| Net Cash Provided by (Used in) Investing Activities | 377.18M | 363.44M | 239.57M | 243.26M | 1.25B | 75.75M |
| Net Cash Provided by (Used in) Financing Activities | 8.68M | 14.44M | 5.43M | 2.35M | -765.77M | 261.52M |
Derived Metrics
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Free Cash Flow | -119.69M | -97.33M | -279.96M | -190.25M | -112.25M | -134.13M |
| Working Capital | 776.00M | 859.85M | 958.35M | 949.05M | 916.25M | 884.44M |
| Net Debt | -77.86M | -48.92M | -48.20M | -32.11M | -26.02M | -19.26M |
| Gross Margin | 93.64% | 90.59% | 86.96% | 86.33% | 87.57% | 88.26% |
| Operating Margin | -530.34% | -608.89% | -907.37% | -1020.12% | -1221.97% | -1165.30% |
| Net Margin | -477.74% | -541.09% | -803.05% | -899.40% | -1023.25% | -899.56% |
| Return on Equity (ROE) | -8.94% | -9.06% | -8.05% | -8.18% | -6.09% | -6.26% |
| Return on Assets (ROA) | -8.36% | -8.33% | -7.46% | -7.61% | -5.74% | -5.80% |
| Current Ratio | 14.19× | 11.46× | 13.82× | 14.48× | 18.50× | 11.90× |
| Debt-to-Equity | 0.03× | 0.03× | 0.03× | 0.04× | 0.04× | 0.04× |
| Effective Tax Rate | — | 0.93% | 0.00% | — | — | 8.42% |
| Cash Conversion Ratio | 1.20× | 0.89× | 2.68× | 1.68× | 1.25× | 1.38× |
| Accruals Ratio | 0.02× | -0.01× | 0.13× | 0.05× | 0.01× | 0.02× |
| SBC % of Revenue | 74.91% | 70.74% | 298.35% | 209.16% | 130.17% | 101.61% |
| CapEx Coverage | -154.64× | -85.90× | -86.60× | -114.94× | -145.55× | -137.71× |
| Free Cash Flow Per Share | $-2.04 | $-1.68 | $-4.82 | $-3.28 | $-1.95 | $-2.32 |
Valuation Metrics
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| P/E Trailing (Diluted) | — | — | — | 3.02× | 2.61× | 2.90× |
| P/S | 30.39× | 29.45× | 52.23× | 47.23× | 45.80× | 51.46× |
| P/B | 1.81× | 1.33× | 1.82× | 1.41× | 1.16× | 1.22× |
Income Statement
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Revenue from Contract with Customer, Excluding Assessed Tax | 20.75M | 19.97M | 12.88M | 12.46M | 8.73M | 10.73M |
| Cost of Goods and Services Sold | 1.32M | 1.88M | 1.68M | 1.70M | 1.08M | 1.26M |
| Research and Development Expense | 81.15M | 88.06M | 86.80M | 91.94M | 72.74M | 82.81M |
| Selling, General and Administrative Expense | 48.30M | 51.61M | 41.27M | 45.87M | 41.53M | 51.70M |
| Operating Income (Loss) | -110.03M | -121.58M | -116.87M | -127.06M | -106.63M | -125.04M |
| Income Tax Expense (Benefit) | — | -1.02M | 0 | — | — | -8.88M |
| Net Income (Loss) Attributable to Parent | -99.11M | -108.04M | -103.43M | -112.02M | -89.29M | -96.52M |
| Earnings Per Share, Basic | $-1.69 | $-1.85 | $-1.78 | $-1.93 | $-1.55 | $-1.72 |
| Weighted Average Number of Shares Outstanding, Basic | 58.78M | 57.97M | 58.14M | 57.93M | 57.46M | 56.81M |
| Earnings Per Share, Diluted | $-1.69 | $-1.85 | $-1.78 | $-1.93 | $-1.55 | $-1.74 |
| Weighted Average Number of Shares Outstanding, Diluted | 58.78M | 57.97M | 58.14M | 57.93M | 57.46M | 57.89M |
Balance Sheet
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Cash and Cash Equivalents, at Carrying Value | 113.60M | 89.13M | 92.71M | 80.87M | 78.96M | 76.25M |
| Assets, Current | 834.84M | 942.05M | 1.03B | 1.02B | 968.62M | 965.60M |
| Assets | 1.18B | 1.30B | 1.39B | 1.47B | 1.56B | 1.66B |
| Liabilities, Current | 58.84M | 82.21M | 74.76M | 70.41M | 52.37M | 81.16M |
| Liabilities | 75.88M | 104.11M | 101.38M | 101.68M | 88.99M | 122.24M |
| Stockholders' Equity Attributable to Parent | 1.11B | 1.19B | 1.28B | 1.37B | 1.47B | 1.54B |
| Common Stock, Shares, Outstanding | 59.34M | 58.45M | 58.28M | 58.04M | 57.89M | 57.16M |
Cash Flow Statement
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Net Cash Provided by (Used in) Operating Activities | -118.92M | -96.21M | -276.76M | -188.61M | -111.49M | -133.17M |
| Payments to Acquire Property, Plant, and Equipment | 769.00K | 1.12M | 3.20M | 1.64M | 766.00K | 967.00K |
| Net Cash Provided by (Used in) Investing Activities | 141.31M | 90.08M | 287.11M | 191.55M | 112.59M | -49.16M |
| Net Cash Provided by (Used in) Financing Activities | 2.08M | 2.56M | 6.12M | 1.68M | 1.62M | 4.84M |
Raw XBRL tagging for a single filing
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Methodology
All facts on this page come straight from SEC EDGAR XBRL
company-facts filings (AGIO CIK 0001439222),
grouped by financial statement using FASB's base
us-gaap presentation taxonomy. Filers may re-parent
concepts onto different statements in their own extension
taxonomy, so a handful of rows can show up under a different
statement than on the actual 10-K / 10-Q; custom concepts and
any we couldn't map fall into Other. Hover a
cell to see the fully-qualified concept name and the filer's
description.
For the full methodology — statement grouping, the Other bucket, derived metrics, and fact tooltips — see the methodology reference for the statement grouping, the "Other" bucket, derived metrics, and fact tooltips.