Syndax Pharmaceuticals, Inc. financials
Source: EDGAR filings · Built 2026-06-02T04:04:19Z
Key metrics by reporting period
Up to six most-recent periods side-by-side. Rows are the curated key lines — revenue, margins, cash, debt, equity, cash-flow totals, plus the derived and valuation metrics we compute on top. For every tag a filer reported in one period, use the single-filing drilldown below.
Derived Metrics
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Free Cash Flow | -323.17M | -274.90M | -160.60M | -133.68M | 29.00M | -71.26M |
| EBITDA | -267.08M | -331.67M | -217.95M | -118.76M | 69.22M | -71.33M |
| Working Capital | 407.96M | 499.51M | 522.78M | 460.72M | 427.71M | 279.99M |
| Net Debt | 216.59M | 191.65M | -293.78M | -73.21M | -220.89M | -114.83M |
| Operating Margin | -158.45% | -1434.43% | — | — | 18.77% | -4708.17% |
| Net Margin | -165.60% | -1346.11% | — | — | 17.84% | -4822.54% |
| Return on Equity (ROE) | -441.62% | -110.63% | -37.78% | -31.95% | 6.10% | -29.01% |
| Return on Assets (ROA) | -53.88% | -43.98% | -34.16% | -30.03% | 5.54% | -24.34% |
| Current Ratio | 4.40× | 5.82× | 10.00× | 16.85× | 21.68× | 15.84× |
| Debt-to-Equity | 5.44× | 1.20× | 0.00× | 0.00× | 0.00× | 0.00× |
| Cash Conversion Ratio | 1.13× | 0.86× | 0.77× | 0.90× | 1.17× | 0.97× |
| Accruals Ratio | 0.07× | -0.06× | -0.08× | -0.03× | -0.01× | -0.01× |
| SBC % of Revenue | 27.56% | 181.70% | — | — | 9.53% | 597.03% |
| CapEx Coverage | -1727.17× | — | — | — | 225.82× | — |
| Free Cash Flow Per Share | $-3.73 | $-3.21 | $-2.28 | $-2.20 | $0.54 | $-1.73 |
Valuation Metrics
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| P/E Trailing (Diluted) | — | — | — | — | 47.59× | — |
| P/FCF | — | — | — | — | 40.47× | — |
| FCF Yield | — | — | — | — | 2.47% | — |
| EV / EBITDA | — | — | — | — | 14.20× | — |
| P/S | 10.65× | 47.84× | — | — | 8.61× | 701.96× |
| P/B | 28.41× | 3.93× | 3.31× | 3.71× | 2.95× | 4.22× |
Income Statement
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Revenue from Contract with Customer, Excluding Assessed Tax | 172.35M | 23.68M | 0 | 0 | 139.71M | 1.52M |
| Research and Development Expense | 258.78M | 241.65M | 163.03M | 118.50M | 88.25M | 50.44M |
| Selling, General and Administrative Expense | 179.68M | 120.88M | 66.92M | 33.26M | 25.24M | — |
| Operating Expenses | 445.44M | 363.35M | 229.95M | 151.76M | 113.49M | 72.94M |
| Operating Income (Loss) | -273.08M | -339.67M | -229.95M | -151.76M | 26.22M | -71.42M |
| Income Tax Expense (Benefit) | 433.00K | — | — | — | 0 | 0 |
| Net Income (Loss) Attributable to Parent | -285.42M | -318.76M | -209.36M | -149.34M | 24.93M | -73.16M |
| Earnings Per Share, Basic | $-3.29 | $-3.72 | $-2.98 | $-2.46 | $0.48 | $-1.87 |
| Weighted Average Number of Shares Outstanding, Basic | 86.63M | 85.62M | 70.37M | 60.76M | 52.06M | 41.31M |
| Earnings Per Share, Diluted | $-3.29 | $-3.72 | $-2.98 | $-2.46 | $0.46 | $-1.87 |
| Weighted Average Number of Shares Outstanding, Diluted | 86.63M | 85.62M | 70.37M | 60.76M | 53.62M | 41.31M |
Balance Sheet
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Cash and Cash Equivalents, at Carrying Value | 134.93M | 154.08M | 295.39M | 74.36M | 221.97M | 115.24M |
| Assets, Current | 528.08M | 603.06M | 580.88M | 489.79M | 448.40M | 298.86M |
| Assets | 529.71M | 724.82M | 612.88M | 497.24M | 449.66M | 300.61M |
| Liabilities, Current | 120.12M | 103.55M | 58.10M | 29.07M | 20.68M | 18.87M |
| Liabilities | 465.08M | 436.69M | 58.68M | 29.79M | 41.29M | 48.42M |
| Stockholders' Equity Attributable to Parent | 64.63M | 288.12M | 554.20M | 467.45M | 408.37M | 252.19M |
| Common Stock, Shares, Outstanding | 87.41M | 85.69M | 84.83M | 68.11M | 54.98M | 47.88M |
Cash Flow Statement
| Concept | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Net Cash Provided by (Used in) Operating Activities | -322.98M | -274.90M | -160.60M | -133.68M | 29.13M | -71.26M |
| Payments to Acquire Property, Plant, and Equipment | 187.00K | 0 | 0 | 0 | 129.00K | 0 |
| Net Cash Provided by (Used in) Investing Activities | 290.04M | -219.78M | 117.61M | -186.19M | -40.87M | -142.53M |
| Net Cash Provided by (Used in) Financing Activities | 13.68M | 353.37M | 264.13M | 172.25M | 118.46M | 304.42M |
Derived Metrics
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| EBITDA | -30.20M | — | — | — | -83.76M | — |
| Working Capital | 385.00M | 407.96M | 415.64M | 418.69M | 454.20M | 499.51M |
| Net Debt | 219.59M | 216.59M | 227.43M | 235.56M | 190.18M | 191.65M |
| Operating Margin | -52.73% | -91.01% | -125.19% | -182.71% | -417.91% | -1254.75% |
| Net Margin | -65.79% | -98.96% | -132.36% | -189.28% | -423.34% | -1226.16% |
| Return on Equity (ROE) | -102.53% | -105.24% | -52.60% | -45.64% | -39.45% | -32.68% |
| Return on Assets (ROA) | -9.03% | -12.84% | -11.00% | -12.05% | -13.24% | -12.99% |
| Current Ratio | 5.47× | 4.40× | 4.64× | 4.71× | 5.80× | 5.82× |
| Debt-to-Equity | 8.42× | 5.44× | 2.98× | 2.19× | 1.60× | 1.20× |
| Cash Conversion Ratio | 1.18× | 1.02× | 4.18× | 2.55× | 1.12× | 0.61× |
| Accruals Ratio | 0.02× | 0.00× | 0.35× | 0.19× | 0.02× | -0.05× |
| SBC % of Revenue | 18.58% | 16.37% | 79.02% | 63.67% | 51.79% | 160.12% |
Valuation Metrics
Income Statement
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Revenue from Contract with Customer, Excluding Assessed Tax | 64.86M | 68.73M | 45.87M | 37.96M | 20.04M | 7.68M |
| Research and Development Expense | 58.84M | 78.64M | 56.28M | 62.23M | 61.64M | 65.53M |
| Operating Expenses | 99.07M | 131.28M | 103.30M | 107.31M | 103.80M | 104.05M |
| Operating Income (Loss) | -34.20M | -62.55M | -57.43M | -69.35M | -83.76M | -96.36M |
| Income Tax Expense (Benefit) | 0 | 433.00K | 0 | 0 | 0 | — |
| Net Income (Loss) Attributable to Parent | -42.67M | -68.01M | -60.72M | -71.85M | -84.85M | -94.17M |
| Earnings Per Share, Basic | $-0.48 | $-0.78 | $-0.70 | $-0.83 | $-0.98 | $-1.09 |
| Weighted Average Number of Shares Outstanding, Basic | 88.26M | 86.63M | 86.62M | 86.34M | 86.17M | 85.62M |
| Earnings Per Share, Diluted | $-0.48 | $-0.78 | $-0.70 | $-0.83 | $-0.98 | $-1.09 |
| Weighted Average Number of Shares Outstanding, Diluted | 88.26M | 86.63M | 86.62M | 86.34M | 86.17M | 85.62M |
Balance Sheet
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Cash and Cash Equivalents, at Carrying Value | 130.89M | 134.93M | 116.81M | 108.64M | 153.99M | 154.08M |
| Assets, Current | 471.18M | 528.08M | 529.83M | 531.68M | 548.75M | 603.06M |
| Assets | 472.67M | 529.71M | 551.79M | 596.15M | 640.71M | 724.82M |
| Liabilities, Current | 86.17M | 120.12M | 114.19M | 112.99M | 94.55M | 103.55M |
| Liabilities | 431.05M | 465.08M | 436.36M | 438.73M | 425.65M | 436.69M |
| Stockholders' Equity Attributable to Parent | 41.62M | 64.63M | 115.43M | 157.42M | 215.06M | 288.12M |
| Common Stock, Shares, Outstanding | 88.54M | 87.41M | 86.91M | 86.06M | 86.05M | 85.69M |
Cash Flow Statement
| Concept | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|
| Net Cash Provided by (Used in) Operating Activities | -50.34M | -69.49M | -253.49M | -182.96M | -95.16M | -57.39M |
| Net Cash Provided by (Used in) Investing Activities | 38.39M | 81.58M | 208.46M | 136.03M | 94.14M | -268.97M |
| Net Cash Provided by (Used in) Financing Activities | 7.92M | 5.92M | 7.76M | 1.48M | 930.00K | 347.43M |
Raw XBRL tagging for a single filing
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Methodology
All facts on this page come straight from SEC EDGAR XBRL
company-facts filings (SNDX CIK 0001395937),
grouped by financial statement using FASB's base
us-gaap presentation taxonomy. Filers may re-parent
concepts onto different statements in their own extension
taxonomy, so a handful of rows can show up under a different
statement than on the actual 10-K / 10-Q; custom concepts and
any we couldn't map fall into Other. Hover a
cell to see the fully-qualified concept name and the filer's
description.
For the full methodology — statement grouping, the Other bucket, derived metrics, and fact tooltips — see the methodology reference for the statement grouping, the "Other" bucket, derived metrics, and fact tooltips.