Karyopharm Therapeutics Inc. (KPTI) Stock Total Returns

Growth of $10,000 chart

2021-06-03 to 2026-06-03
to
$
%
%
Loading chart…

Investment Performance

Final Value
$649
Total Return
-93.51%
CAGR
-42.14%
Dividends
$0.00
Yield on Cost
0.00%

Rolling Returns

1-Month (21 Trading Days)
Average-1.68%
Median-5.04%
Best+101.95%
Worst-55.75%
% of Windows Positive39.8%
1-Year (252 Trading Days)
Average-42.66%
Median-52.31%
Best+119.77%
Worst-87.62%
% of Windows Positive10.7%
3-Year (756 Trading Days)
Average-89.44%
Median-90.40%
Best-73.81%
Worst-96.79%
% of Windows Positive0.0%

Risk Metrics

Maximum Drawdown -98.36%
Average Drawdown -78.16%
Drawdown Duration 1074 Trading Days (Unrecovered)
Sortino Ratio -0.16
Calmar Ratio -0.43
CVaR (5%) -12.29%

Yearly Returns

Year Percentage Abs. Return Dividends Taxes Trans. Costs
2026 partial +22.28% (+61.14% ann.) +$2228.26 $0.00 $0.00 $0.00
2025 -27.42% $2741.58 $0.00 $0.00 $0.00
2024 -21.85% $2185.03 $0.00 $0.00 $0.00
2023 -74.56% $7455.89 $0.00 $0.00 $0.00
2022 -47.12% $4712.29 $0.00 $0.00 $0.00
2021 -58.46% $5846.25 $0.00 $0.00 $0.00
2020 -19.25% $1924.88 $0.00 $0.00 $0.00
2019 +104.59% +$10458.89 $0.00 $0.00 $0.00
2018 -2.40% $239.58 $0.00 $0.00 $0.00
2017 +2.13% +$212.76 $0.00 $0.00 $0.00
2016 -29.06% $2905.66 $0.00 $0.00 $0.00
2015 -64.60% $6460.06 $0.00 $0.00 $0.00
2014 +63.31% +$6330.72 $0.00 $0.00 $0.00
2013 partial +42.80% (+965.64% ann.) +$4280.37 $0.00 $0.00 $0.00

Market Regimes

about
Regime Period Percentage Annual Abs. Return Dividends Taxes Trans. Costs
Secular stagnation / QE / low inflation / duration bull partial November 6, 2013 – February 19, 2020 +1.68% +0.27% +$168.22 $0.00 $0.00 $0.00
Pandemic shock / liquidity crash February 20, 2020 – March 23, 2020 +11.40% +242.73% +$1139.55 $0.00 $0.00 $0.00
Policy bazooka / monetary euphoria March 24, 2020 – November 6, 2020 -30.12% -43.83% $3012.34 $0.00 $0.00 $0.00
Reopening reflation / fiscal boom / supply bottlenecks November 9, 2020 – November 29, 2021 -53.02% -51.16% $5301.79 $0.00 $0.00 $0.00
Inflation shock / duration crash / aggressive tightening November 30, 2021 – November 9, 2022 -22.16% -23.35% $2215.82 $0.00 $0.00 $0.00
Disinflation rebound / AI-led narrow bull / higher-for-longer November 10, 2022 – September 17, 2024 -86.93% -66.65% $8693.38 $0.00 $0.00 $0.00
Disinflationary easing / resilient growth / AI capex under oil-shock test partial September 18, 2024 – June 3, 2026 -18.59% -11.36% $1858.93 $0.00 $0.00 $0.00

Dividend History

Date Per Share Yield %
Total 0 payments
No dividends recorded.

All calculations use split-adjusted closing prices. Dividends are reinvested on the ex-dividend date at that day's closing price.

For each rolling window, returns are calculated at every possible starting point:

return = (value[i] ÷ value[i − windowSize] − 1) × 100

Windows
1-month = 21 trading days, 1-year = 252 trading days, 3-year = 756 trading days.
Statistics
Average: arithmetic mean. Median: middle value when sorted. Best / Worst: max and min. % Positive: share of windows with return > 0.

The series is segmented by calendar year:

return = (endValue ÷ startValue − 1) × 100

startValue is the last value of the prior year (or the first value for the initial year). Partial first/last years are flagged. Dividends, taxes, and transaction costs are scaled proportionally to the initial investment.

SKIL

CAGR -38.32% Total -96.36% Final $364.14
2019-07-26 — 2026-06-03
BUR

CAGR -13.44% Total -55.58% Final $4,442
2020-10-19 — 2026-06-03
JILL

CAGR -13.83% Total -74.70% Final $2,530
2017-03-09 — 2026-06-03