SPYRE THERAPEUTICS, INC. (SYRE) capitalization

Current snapshot

Market Cap
$4.38B
86.8M shares × $50.44 · as of last filing 2026-03-31
Net Worth
$670.8M
Stockholders' equity · 2026-03-31
Enterprise Value
$4.28B
Market cap + debt − cash
Net Debt
-$97.2M
Debt — − Cash $97.2M

Annual history

One row per fiscal year (10-K). Market cap uses split-adjusted closing price on the fiscal-year-end date × shares outstanding.

Period End Market Cap
FY'25 2025-12-31 $2.56B
FY'24 2024-12-31 $1.40B
FY'23 2023-12-31 $148.4M
FY'22 2022-12-31
FY'21 2021-12-31
FY'20 2020-12-31
FY'19 2019-12-31
FY'18 2018-12-31
FY'17 2017-12-31
FY'16 2016-12-31
FY'16 2015-12-31
FY'16 2014-12-31

Quarterly history

One row per quarter (10-Q and Q4 from 10-K). Market cap uses split-adjusted closing price on the quarter-end date × shares outstanding.

Period End Market Cap
Q1'26 2026-03-31 $3.98B
Q4'25 2025-12-31 $2.56B
Q3'25 2025-09-30 $1.01B
Q2'25 2025-06-30 $903.8M
Q1'25 2025-03-31 $972.5M
Q4'24 2024-12-31 $1.40B
Q3'24 2024-09-30 $1.50B
Q2'24 2024-06-30 $1.07B
Q1'24 2024-03-31 $1.38B
Q4'23 2023-12-31 $775.9M
Q3'23 2023-09-30
Q2'23 2023-06-30
Q1'23 2023-03-31
Q4'22 2022-12-31
Q3'22 2022-09-30
Q2'22 2022-06-30
Q1'22 2022-03-31
Q4'21 2021-12-31
Q3'21 2021-09-30
Q2'21 2021-06-30
Q1'21 2021-03-31
Q4'20 2020-12-31
Q3'20 2020-09-30
Q2'20 2020-06-30
Q1'20 2020-03-31
Q4'19 2019-12-31
Q3'19 2019-09-30
Q2'19 2019-06-30
Q1'19 2019-03-31
Q4'18 2018-12-31
Q3'18 2018-09-30
Q2'18 2018-06-30
Q1'18 2018-03-31
Q4'17 2017-12-31
Q3'17 2017-09-30
Q2'17 2017-06-30
Q1'17 2017-03-31
Q4'16 2016-12-31
Q3'16 2016-09-30
Q2'16 2016-06-30
Q1'16 2016-03-31
Q4'16 2015-12-31
Q3'16 2015-09-30
Q2'16 2015-06-30
Q1'16 2015-03-31

Methodology

Every figure on this page traces back to SEC EDGAR XBRL company-facts filings (SYRE CIK 0001636282), tagged with the us-gaap and dei taxonomies. Filing-anchored figures are rendered server-side: the market cap and enterprise value tiles use the split-adjusted close on the latest reported period-end × shares outstanding, so they reconcile with the equity / debt / cash figures from that same filing. The two price-anchored tiles (market cap + enterprise value) re-anchor on the most recent daily close in the browser when JavaScript is enabled; shares outstanding and debt / cash stay filing-anchored, so the EV bridge still uses the latest statement of financial position. Historical share prices come from our total-returns daily history (split-adjusted); historical market caps are calibrated against today's share count to correct for SEC retroactive split restatements.

For the exact XBRL concepts and formulas, see the methodology reference for net worth, debt, cash, market cap, enterprise value, net debt, shares outstanding, and the historical-market-cap calibration.

Related tickers

PEBK

PEOPLES BANCORP OF NORTH CAROLINA, INC.

AGIO

AGIOS PHARMACEUTICALS, INC.

FNWD

Finward Bancorp