Spyre Therapeutics, Inc. (SYRE) Stock Total Returns

Growth of $10,000 chart

2021-06-03 to 2026-06-03
to
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Investment Performance

Final Value
$4,389
Total Return
-56.11%
CAGR
-15.19%
Dividends
$0.00
Yield on Cost
0.00%

Rolling Returns

1-Month (21 Trading Days)
Average+6.29%
Median-1.01%
Best+459.41%
Worst-74.68%
% of Windows Positive48.2%
1-Year (252 Trading Days)
Average+62.64%
Median-10.73%
Best+1033.77%
Worst-94.32%
% of Windows Positive45.9%
3-Year (756 Trading Days)
Average+138.05%
Median-54.88%
Best+2078.34%
Worst-87.99%
% of Windows Positive42.6%

Risk Metrics

Maximum Drawdown -98.74%
Average Drawdown -78.84%
Drawdown Duration 1162 Trading Days (Unrecovered)
Sortino Ratio 1.10
Calmar Ratio -0.15
CVaR (5%) -12.77%

Yearly Returns

Year Percentage Abs. Return Dividends Taxes Trans. Costs
2026 partial +124.42% (+580.19% ann.) +$12441.98 $0.00 $0.00 $0.00
2025 +40.72% +$4072.20 $0.00 $0.00 $0.00
2024 +8.18% +$817.88 $0.00 $0.00 $0.00
2023 +91.29% +$9128.94 $0.00 $0.00 $0.00
2022 -90.53% $9052.64 $0.00 $0.00 $0.00
2021 -39.64% $3964.42 $0.00 $0.00 $0.00
2020 +3.01% +$301.04 $0.00 $0.00 $0.00
2019 +2.00% +$200.27 $0.00 $0.00 $0.00
2018 +38.45% +$3844.74 $0.00 $0.00 $0.00
2017 +24.37% +$2436.77 $0.00 $0.00 $0.00
2016 partial -55.48% (-66.94% ann.) $5547.59 $0.00 $0.00 $0.00

Market Regimes

about
Regime Period Percentage Annual Abs. Return Dividends Taxes Trans. Costs
Secular stagnation / QE / low inflation / duration bull partial April 7, 2016 – February 19, 2020 -15.86% -4.37% $1586.49 $0.00 $0.00 $0.00
Pandemic shock / liquidity crash February 20, 2020 – March 23, 2020 -48.33% -99.95% $4832.71 $0.00 $0.00 $0.00
Policy bazooka / monetary euphoria March 24, 2020 – November 6, 2020 +91.22% +183.80% +$9122.41 $0.00 $0.00 $0.00
Reopening reflation / fiscal boom / supply bottlenecks November 9, 2020 – November 29, 2021 -28.89% -27.63% $2888.89 $0.00 $0.00 $0.00
Inflation shock / duration crash / aggressive tightening November 30, 2021 – November 9, 2022 -79.17% -81.09% $7916.67 $0.00 $0.00 $0.00
Disinflation rebound / AI-led narrow bull / higher-for-longer November 10, 2022 – September 17, 2024 -25.95% -14.96% $2594.77 $0.00 $0.00 $0.00
Disinflationary easing / resilient growth / AI capex under oil-shock test partial September 18, 2024 – June 3, 2026 +153.87% +72.67% +$15386.74 $0.00 $0.00 $0.00

Dividend History

Date Per Share Yield %
Total 0 payments
No dividends recorded.

All calculations use split-adjusted closing prices. Dividends are reinvested on the ex-dividend date at that day's closing price.

For each rolling window, returns are calculated at every possible starting point:

return = (value[i] ÷ value[i − windowSize] − 1) × 100

Windows
1-month = 21 trading days, 1-year = 252 trading days, 3-year = 756 trading days.
Statistics
Average: arithmetic mean. Median: middle value when sorted. Best / Worst: max and min. % Positive: share of windows with return > 0.

The series is segmented by calendar year:

return = (endValue ÷ startValue − 1) × 100

startValue is the last value of the prior year (or the first value for the initial year). Partial first/last years are flagged. Dividends, taxes, and transaction costs are scaled proportionally to the initial investment.

BALY

CAGR -17.76% Total -25.27% Final $7,473
2024-12-06 — 2026-06-03
HUBS

CAGR 18.73% Total 639.04% Final $73,904
2014-10-09 — 2026-06-03
RNR

CAGR 13.97% Total 5553.33% Final $565,333
1995-07-27 — 2026-06-03